Aspirin acetylates nitric oxide synthase type 3 in platelets thereby increasing its activity
نویسندگان
چکیده
منابع مشابه
Aspirin modifies nitric oxide synthase activity in platelets: effects of acute versus chronic aspirin treatment.
OBJECTIVE We examined the effects of aspirin on basal and beta-adrenoceptor (beta-AR)-mediated nitric oxide synthase (NOS) activity in normal platelets. METHODS NOS activity was determined from the conversion of L-[3H]arginine to L-[3H]citrulline, both basally and following beta-AR stimulation, in platelets from healthy human subjects following both short- and long-term aspirin administration...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2009
ISSN: 0008-6363
DOI: 10.1093/cvr/cvp120